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Higher odd ratios of negative effects by HRT, such as irregular bleeds, weight gain, food craving and skin disorders were also found in CYC-TRANS group.

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Risk associated with hormone replacement therapy for the different endpoints in total population as well as in four specified subsets during randomisation phase (up to year 2002).

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Publishing the results of the estrogen-only arm of WHI.

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In most cases, women experience shrinkage of fibroids after menopause, but if they are taking hormone replacement therapy, women are not likely to experience any lessening of the symptoms of fibroid growth, notes Cedars-Sinai.

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